An open-label, exploratory documentation of proving-symptoms of CVN01 (Coronavirus nosode from the clinical sample) in healthy volunteers

INTRODUCTION Homeopathic Pathogenetic Trials (Proving) are human studies to examine the pathogenetic effects of investigational drugs in high dilution on healthy volunteers. As a part new coronavirus nosode development process for prophylactic use, phase 1 study was conducted. The documentation proving symptoms fast-track pandemic condition objectives this study. MATERIALS AND METHODS An open-label trial evaluate safety and Coronavirus given orally 10 volunteers (18-65 years age both genders). Volunteers were administered 6 doses as pills twice daily 3 consecutive days. Pre post examinations (physical), vital signs, laboratory investigations, done at day 0, 17, 34. Symptoms experienced by recorded. RESULTS reported analyzed. mild severe but reversible matching with produced viral infection. There no serious/fatal adverse events during basic biochemistry Liver Function tests not affected Nosode. CONCLUSION New developed certain homeopathic Phase